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Figure 1: Expression of dormancy and metabolic shift genetic markers by adipocyte-dwelling M. tuberculosis. Graph shows the expression of three key genes associated to dormancy (dosR) and metabolism (icl and citA) by intra-adipocyte bacilli. The log2-Fold change for each time-point is relative to in vitro growing (exponential phase) bacilli. The values plotted are the mean ± standard deviation of triplicate experiments in three biological replicates. |
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