Close
  Indian J Med Microbiol
 

Figure 3: Transmission electron micrographs of NCF cells exposed to 10× MBC of rifampicin. (a) Transmission electron micrographs of M. smegmatis NCF cells exposed to 25 μg/ml of rifampicin for 72 h. (i-iii) Longitudinal sections of M. smegmatis NCF cells with multiple septae (black arrows). (iv-vi) Longitudinal sections of M. smegmatis NCF cells with multiple nucleoids (red arrows). (b-d) Quantitation of the TEM data of the NCF cells with multiple nucleoids, multiple septae or nil septum. Percentage of NCF cells: (b) with single or multiple nucleoids (n = 409); (c) with single or multiple septae (n = 67); (d) with or without septum/septae out of the total number of septated and nonseptated cells (n = 409 cells), MBC: Minimum bactericidal concentration, NCF: Normal-sized cells-enriched fraction, TEM: Transmission electron microscopy

Figure 3: Transmission electron micrographs of NCF cells exposed to 10× MBC of rifampicin. (a) Transmission electron micrographs of <i>M. smegmatis</i> NCF cells exposed to 25 μg/ml of rifampicin for 72 h. (i-iii) Longitudinal sections of <i>M. smegmatis</i> NCF cells with multiple septae (black arrows). (iv-vi) Longitudinal sections of <i>M. smegmatis</i> NCF cells with multiple nucleoids (red arrows). (b-d) Quantitation of the TEM data of the NCF cells with multiple nucleoids, multiple septae or nil septum. Percentage of NCF cells: (b) with single or multiple nucleoids (<i>n</i> = 409); (c) with single or multiple septae (<i>n</i> = 67); (d) with or without septum/septae out of the total number of septated and nonseptated cells (<i>n</i> = 409 cells), MBC: Minimum bactericidal concentration, NCF: Normal-sized cells-enriched fraction, TEM: Transmission electron microscopy